Estrogenic endocrine disruptors present in sports supplements. A risk assessment for human health
Food Chemistry Volume 159, 15 September 2014, Pages 157–165 Monika Plotan
• Estrogenic activity is quantified in sports supplements and an exposure and risk assessment performed.
• 17β-Estradiol equivalent activity levels were higher than the ADI in 26% of exposure assessment samples.
• 17β-Estradiol equivalent activity levels were higher in 66% of exposure assessment samples than levels present in the typical diet.
• The predicted hormonal impact of greatest concern is for young boys and postmenopausal women.
• Consumers of sport supplements may be exposed to high levels of estrogenic endocrine disruptors.
Sports supplements are becoming a regular dietary addition for consumers who view such products as a means of improving their health and performance. Previously estrogenic endocrine disruptors (EDs) were detected in 80% of 116 sports supplements investigated by biological in vitro reporter gene assays (RGAs). The aim of this study was to quantify the hormonal activity in 50 of these sports supplement samples using a validated estrogen RGA and perform an exposure and risk assessment for human health.
Results showed that 17β-estradiol equivalent levels were higher than those reported as being present in the typical human omnivore diet in 33 of the sports supplements and higher than the acceptable daily intake (ADI) in 13 of these products. The highest activity samples presented a potential to influence the human daily exposure to 17β-estradiol like activity in various risk groups with a predicted hormonal impact of greatest concern in young boys and postmenopausal women.
In conclusion, consumers of sports supplements may be exposed to high levels of estrogenic EDs.
Voir aussi :
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- De nouvelles cellules souches découvertes dans les muscles
- 80% des suppléments européens de rhodiole sont de mauvaise qualité
- La natation: pas super efficace dans la chasse au gras
- Des hormones thyroïdiennes dans les suppléments boosters de thyroïde?