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Influence de la sérine sur la sécrétion de GH et cortisol?

28/03/2018 | Etudes Compléments alimentaires et Etudes Perte de poids et Etudes Anti-âge

 

Effects of L-serine supplementation on the daily rhythms of growth hormone and corticosterone concentrations in mice
Li Wu,      Biological Rhythm Research       22 Mar 2018    

The impact of L-serine on the daily rhythms of growth hormone (GH) and corticosterone remains unknown. We explored whether the daily rhythms of these hormones were affected by L-serine supplementation as well as the supplementation time.

The results showed that plasma GH concentration at Zeitgeber time (ZT) 4 and 8 were significantly increased by L-serine supplementation at ZT22, while the diurnal rhythms peaks of plasma corticosterone at ZT12 were suppressed by L-serine supplementation at ZT10. After the supplementation was stopped, the effects of L-serine on the diurnal rhythms of plasma GH and corticosterone lasted for 2 days then they were fading on day 4. L-serine concentrations in plasma and hypothalamus after supplementation at ZT22 was lower than those after supplementation at ZT10.

In conclusion, L-serine modulates the daily rhythms of GH and corticosterone depending on its supplementation time. The modulation effect might be association with the daily rhythms of L-serine metabolism.

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