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Blancs d’oeufs VS blancs + jaunes sur l’anabolisme?

23/08/2018 | Etudes Compléments alimentaires

 

Il me semble y avoir un gros biais calorique

Whole egg, but not egg white ingestion, induces mTOR co-localization with the lysosome after resistance exercise in trained young men
Sidney Abou Sawan

We have recently demonstrated that whole egg ingestion induces a greater muscle protein synthetic (MPS) response when compared to isonitrogenous egg white ingestion after resistance exercise in young men. Our aim was to determine whether whole egg or egg white ingestion differentially influenced co-localization of key regulators of mechanistic target of rapamycin complex 1 (mTORC1) as means to explain our previously observed divergent post-exercise MPS response. In crossover trials, 10 healthy resistance-trained men (21±1 y; 88±3 kg; body fat: 16±1 %; means±SEM) completed lower body resistance exercise before ingesting whole eggs (18 g protein, 17 g fat) or egg whites (18 g protein, 0 g fat). Muscle biopsies were obtained before exercise and at 120 and 300 min after egg ingestion to assess, by immunofluorescence, protein co-localization of key anabolic signaling molecules. After resistance exercise, TSC2-Rheb co-localization decreased (P<0.01) at 120 and 300 min after whole egg and egg white ingestion with concomitant increases (P<0.01) in mTOR-Rheb co-localization. After resistance exercise, mTOR-LAMP2 co-localization significantly increased at 120 and 300 min only after whole egg ingestion (P<0.01), and mTOR-LAMP2 co-localization correlated with rates of MPS at rest and after exercise (r=0.40, P<0.05).

We demonstrated that the greater post-exercise MPS response with whole egg ingestion is related in part to an enhanced recruitment of mTORC1-Rheb complexes to the lysosome during recovery. These data suggest non-protein dietary factors influence the post-exercise regulation of mRNA translation in human skeletal muscle.

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